BDBM140377 US10947243, Example 102::US8912173, 102::US9914735, Example 102

SMILES COc1cc(ccc1C(F)(F)F)-c1cc(O[C@H](C)[C@H]2CNC(=O)C2)c2cccnc2c1

InChI Key InChIKey=TVBZNTQTCCGAHW-CZUORRHYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 140377   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140377(US10947243, Example 102 | US8912173, 102 | US99147...)
Affinity DataIC50: >1.00E+4nMAssay Description:FLT3 is obtained from Invitrogen in 50 mM Tris (pH7.5); 100 mM NaCl; 0.05 mM EDTA, 0.05% NP-40, 2 mM DTT; 50% Glycerol # PV3182; Lot 286671; sequence...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140377(US10947243, Example 102 | US8912173, 102 | US99147...)
Affinity DataIC50: >1.00E+4nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie—Dept. of Biochemistry) ...More data for this Ligand-Target Pair
In DepthDetails US Patent